It's not exactly manga doujinshi, I think this format is called webcomic or something, but I feel like I must share it.
Meet - Wheelchair Detective Satori by donjuan!
It was made in 2013 by the way.https://youtu.be/B_A5cRts5cIAs you can tell by the name, it is detective story, in each episode you get a riddle to solve (they are too obscure and japanese to actually solve but you might try) and watch Satori solving it, but it also is a funny, sometimes black comedy and a bit of a drama near end. It is very stylish and has neat openings too.
While technically only having 11 episodes, it has sort of second season too - Murder in Pseudo Paradise. Now this is where it jumps from awesome to KINO. Unlike WDS, MiPP has single big connected plotline and you might actually try deducing who's the culprit behind happening events. Openings became even more stylish
https://youtu.be/apoEmBEUj7Y jokes are less numerous and it's more plot-focused. This time, main hero is Kosuzu. While it can be enjoyed as separate story, I highly recommend to first watch WDS to get the atmosphere, and only then MiPP, you will notice more neat details like that as well.
Entire series can (must) be watched here:
https://www.youtube.com/playlist?list=PLl4hOZI8Urbvi41Nt_Lw_SjtrEQx6Eg63